Maple 
Product Specifications
- CAS Number: 53-84-9
- Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
- Molecular Weight: 663.43 g/mol
- Received-sample result: 99.9% HPLC-MS/MS chromatographic relative area (report COA-2026-SC-01771; report lot field 082126), not lot or batch verification.
- Form: Lyophilized powder
- Quantity: 1000mg per vial
Research Summary
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells that functions as a critical electron carrier in metabolic redox reactions. In-vitro studies have extensively characterized its role as a substrate in over 500 enzymatic reactions, including those catalyzed by the sirtuin family of NAD+-dependent deacetylases (SIRT1-7), poly(ADP-ribose) polymerases (PARPs), and CD38/CD157 ectoenzymes. These enzyme families have been investigated for their roles in DNA repair signaling, epigenetic regulation, and cellular stress response pathways in cell culture models.
In animal models, NAD+ metabolism has been studied in the context of age-related decline in intracellular NAD+ levels and its effects on mitochondrial function, genomic stability, and metabolic pathway regulation. Preclinical research has examined the compound’s influence on sirtuin-mediated deacetylation of transcription factors including PGC-1alpha, FOXO, and p53 in rodent tissue models. Researchers have also investigated NAD+ in relation to circadian rhythm signaling, where it serves as a substrate for the SIRT1-mediated regulation of CLOCK-BMAL1 transcriptional activity.
NAD+ serves as a fundamental research tool in cellular metabolism, aging biology, and enzymology studies. Its central role in energy metabolism, redox biology, and cell signaling makes it indispensable for in-vitro investigations across bioenergetics, epigenetics, and related research disciplines.
Storage
Store lyophilized peptide at -20°C. Avoid repeated freeze-thaw cycles.
Shipping
Orders placed by 2 PM PT (Mon–Fri) ship the same business day, from BC with tracking. All orders include temperature-controlled packaging.
Certificate of Analysis (COA)
SideChain Analytics report COA-2026-SC-01771 describes the received NAD+ sample NAD-057_D: 99.9% chromatographic relative-area purity by HPLC-MS/MS and 1211.63 mg measured net content against a 1000 mg label. The report states principal-component confirmation against a reference standard and lists 082126 in its lot field; it expressly does not verify any lot, batch or other supplied vial.
| Testing Laboratory | SideChain Analytics, Mississauga, Ontario (independent third-party laboratory) |
| Report Number | COA-2026-SC-01771 |
| Lot Number | 082126 |
| Method | HPLC-MS/MS (Agilent 1290 Infinity II with 6495 triple quadrupole) |
| Identity | NAD+, principal component confirmed against reference standard |
| Purity (HPLC-MS/MS) | 99.9% |
| Net Content / Fill Accuracy | 1211.63mg measured / 1000mg label (121.2%) |
| Date Analyzed | September 1, 2026 |
| Download COA | Download Full COA (PDF) |
| Verify at the Lab | Open the laboratory’s verification page for this report, or enter the report number at sidechainanalytics.com |
Results are for the sample the laboratory received, reported as measured. The original PDF is also served by the laboratory from its own verification page.
For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.
Related Research Articles
Learn more about this compound through our peer-reviewed research summaries:
- NAD+ vs Glutathione: Cellular Research Comparison
- NAD+ and Longevity Peptides Research
- NAD+ vs SS-31: Mitochondrial Research Comparison
- 5-Amino-1MQ: NNMT Inhibition and NAD+ Rescue
- Certificates of Analysis and Documentation
Related catalogue compounds: SS-31, MOTS-c and 5-Amino-1MQ.
Maple Research Labs supplies NAD+ to research laboratories across Canada for in-vitro study applications.
Join the research list
New arrivals, current pricing, and research breakdowns. New arrivals, current pricing, and research breakdowns. Unsubscribe anytime.
