Peptide Deep Dives

Neuropeptide Y (NPY) is one of the most abundant and widely distributed neuropeptides in the mammalian central nervous system, functioning […]

LEAP-2 (liver-expressed antimicrobial peptide-2) is an endogenous peptide that functions as a competitive antagonist and inverse agonist at the growth

Orexin-A (hypocretin-1) is a 33-amino acid neuropeptide produced exclusively in the lateral hypothalamus that acts as the central coordinator of

Orexin-A (also designated hypocretin-1) is a 33-amino-acid neuropeptide produced exclusively by a compact cluster of lateral hypothalamic neurons. It activates

GLP-2 is a 33-amino acid proglucagon-derived peptide that acts as a potent intestinotrophic hormone through the GLP-2 receptor (GLP-2R), driving

ARA-290 (cibinetide) is an 11-amino acid peptide derived from the helix B region of erythropoietin that selectively activates the innate

Urocortin peptides are endogenous corticotropin-releasing factor (CRF) family ligands that signal through CRF receptor subtypes 1 and 2 (CRFR1 and

Apelin-13 is the most potent endogenous ligand of the APJ receptor (APLNR), a class A GPCR initially classified as an

Liraglutide is a synthetic analog of glucagon-like peptide-1 (GLP-1) engineered with a C-16 fatty acid side chain that dramatically extends

Follistatin-344 is a naturally occurring glycoprotein that functions primarily as a high-affinity antagonist of myostatin (GDF-8) and activin, two members