Peptide Deep Dives

Carnosine (beta-alanyl-L-histidine) research covers reactive carbonyl scavenging, advanced glycation end product inhibition, metal chelation, and neuroprotective mechanisms across Alzheimer’s, Parkinson’s, and metabolic disease preclinical models.

Oxytocin is a nine-amino-acid cyclic neuropeptide (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂) synthesized primarily in the paraventricular and supraoptic nuclei of the hypothalamus. Preclinical research

Cortistatin peptide research covers a neuropeptide structurally related to somatostatin that binds all five somatostatin receptors (SST1-SST5) while also activating

PACAP (Pituitary Adenylate Cyclase-Activating Polypeptide) is a 38-amino acid neuropeptide with potent neuroprotective activity mediated through PAC1, VPAC1, and VPAC2 receptors. This review covers receptor pharmacology, cAMP-PKA-CREB signaling, and preclinical data from ischemia, retinal, and cardiovascular models.

Angiotensin-(1-7) is a biologically active heptapeptide that functions as the primary endogenous ligand for the MAS receptor, a G protein-coupled

GHRP-6 is a synthetic hexapeptide that activates GHS-R1a to stimulate pulsatile growth hormone secretion. This research overview covers receptor pharmacology, preclinical GH data, CD36-mediated cytoprotection, and study design considerations for researchers working with growth hormone secretagogues.

Triptorelin is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) that acts as a potent GnRH receptor agonist, producing paradoxical

Pinealon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland that has demonstrated neuroprotective, antioxidant, and epigenetic regulatory activity

Cagrilintide is a long-acting amylin analog that acts as a non-selective agonist at amylin receptors (AMY1R, AMY2R, AMY3R) and the

5-Amino-1MQ is a selective, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) that rescues intracellular NAD+ and S-adenosylmethionine (SAM) levels by blocking