Maple Body Protection Compound-157, commonly referred to as BPC-157, is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. Over the past two decades, BPC-157 has become one of the most studied peptides in preclinical research.
What Is BPC-157?
BPC-157 is a 15-amino-acid peptide that was first isolated from human gastric juice. Unlike many bioactive peptides, BPC-157 is stable in gastric acid, which has made it a subject of particular interest for gastrointestinal research. Researchers synthesize BPC-157 at purities exceeding 98% as verified by HPLC analysis.
BPC-157 Mechanism of Action
Nitric Oxide System Modulation
Sikiric et al. (2014) demonstrated that BPC-157 modulates NO synthesis in various tissue models (PMID: 24867541).
Growth Factor Upregulation
Chang et al. (2011) observed significant VEGF upregulation in tendon fibroblast cultures treated with BPC-157 (PMID: 21030672).
FAK-Paxillin Pathway
Hsieh et al. (2017) identified the FAK-paxillin signaling pathway as a key mediator of BPC-157 activity (PMID: 28268098).
Key Research Areas
Gastrointestinal Research
Sikiric et al. (1999) documented protective effects against ulcers in rat models (PMID: 10421978).
Musculoskeletal Tissue Repair
Staresinic et al. (2003) demonstrated accelerated muscle healing in rats (PMID: 12911824). Pevec et al. (2010) showed improved tendon healing (PMID: 20225319).
Vascular Effects
Sikiric et al. (2018) documented angiogenic properties across multiple models (PMID: 29898107).
Neurological Research
Tudor et al. (2010) reported neuroprotective effects in demyelination models (PMID: 20388509).
Limitations
Most studies originate from a single research group. Nearly all data is preclinical. Long-term safety data is limited.
BPC-157 Canada: Sourcing
At Maple Research Labs, all BPC-157 is supplied at greater than 98% purity, verified by Janoshik Analytical. COAs are available for every batch on the BPC-157 product page.
Disclaimer: This article is for educational purposes only. BPC-157 is sold strictly as a research chemical. Not intended for human consumption. Maple Research Labs supplies peptides for research use only.