BPC-157 vs TB-500: Understanding Research Differences
A comprehensive comparison of two distinct peptides frequently studied in laboratory research for their unique structural characteristics and biological roles.
Quick Comparison
| Category | BPC-157 | TB-500 |
|---|---|---|
| Compound Type | Synthetic pentadecapeptide | Thymosin beta-4 fragment |
| Amino Acid Length | 15 amino acids | 43 amino acids (active region) |
| Origin | Derived from body protection compound | Derived from thymosin beta-4 |
| Primary Research Focus | Tissue response & signaling pathways | Cell migration & cytoskeletal regulation |
| Research Context | Localized tissue models | Systemic cellular movement models |
| Purity Standard | ≥98% HPLC verified | ≥98% HPLC verified |
| Documentation | Full COA available | Full COA available |
What Is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids, derived from a fragment of a naturally occurring gastric protein. It has become a subject of extensive laboratory research due to its unique structural characteristics.
In laboratory settings, BPC-157 is studied for its role in:
- Cellular signaling pathway research
- Tissue response and repair models
- Nitric oxide system interactions
- Growth factor pathway studies
BPC-157 is commonly utilized in both in-vitro and in-vivo research environments focusing on localized biological response mechanisms and signaling modulation.
What Is TB-500?
TB-500 is a synthetic peptide representing the active region of thymosin beta-4, a naturally occurring 43-amino acid protein. TB-500 contains the specific sequence responsible for the compound's primary biological activities in research models.
In research environments, TB-500 is explored for:
- Cell migration and motility research
- Actin regulation and cytoskeletal studies
- Angiogenesis pathway investigation
- Systemic tissue distribution models
TB-500's unique mechanism involving actin sequestration makes it particularly relevant for research into cellular movement, tissue organization, and vascular development.
Key Differences for Researchers
While often mentioned together, these peptides serve distinct purposes in research settings:
Structural Differences
BPC-157 is a smaller 15-amino acid peptide with a compact structure.TB-500 is larger, representing a 43-amino acid active sequence with different folding characteristics that influence its biological interactions.
Research Application Focus
BPC-157 research typically focuses on localized tissue response models and signaling pathways. TB-500 research often examines broader cellular migration patterns and systemic distribution characteristics.
Mechanism of Action
BPC-157 is studied for interactions with nitric oxide and growth factor systems. TB-500 research focuses on actin-binding properties and cytoskeletal regulation, representing fundamentally different biological mechanisms.
Selection Considerations
The choice between compounds depends on specific research objectives. Studies examining localized tissue responses may favor BPC-157, while research on cellular migration and systemic effects may prefer TB-500. Some protocols examine both compounds comparatively.
Combined Research Approaches
Some research protocols examine BPC-157 and TB-500 in parallel or combination to investigate potential complementary mechanisms:
- Comparative pathway analysis studies
- Multi-compound tissue model research
- Synergistic mechanism investigations
- Localized versus systemic effect comparisons
Maple Research Labs offers both individual compounds and a research blend for investigators conducting comparative or combination studies.
Why Documentation & Testing Matter
In research settings, the reliability of results depends entirely on the quality and consistency of materials used. Third-party verification provides an objective baseline for researchers to trust their experimental inputs.
Third-Party Testing
Independent laboratory verification ensures unbiased purity and identity confirmation.
Batch Consistency
Each production batch is individually tested and documented for reproducibility.
≥98% Purity Standard
HPLC and mass spectrometry verification for research-grade quality assurance.
Transparent COAs
Complete Certificates of Analysis available for every product and batch.
Research-Grade Standards from Maple Research Labs
We're committed to providing researchers with consistently high-quality compounds, transparent documentation, and reliable service across Canada.
Canadian-Based Fulfillment
Fast domestic shipping from within Canada, reducing transit times and customs delays.
Independent Lab Testing
Every batch verified by third-party laboratories for purity and identity confirmation.
Research-Only Compliance
Clear labeling and documentation designed for legitimate research applications.
Consistent Quality Standards
Rigorous QC protocols ensure batch-to-batch consistency for reliable research outcomes.
Frequently Asked Questions
Are BPC-157 and TB-500 the same compound?
No. They are structurally different peptides with distinct research profiles. BPC-157 is a 15-amino acid peptide derived from body protection compound, while TB-500 is a larger fragment derived from thymosin beta-4.
Can they be studied together in research?
Yes. In some experimental designs, researchers may examine both compounds in parallel or in combination to observe different aspects of cellular behavior and compare localized versus systemic effects.
Are these products for human use?
No. All Maple Research Labs peptides are sold strictly for laboratory research use only. They are not approved for human or veterinary use.
What documentation is provided?
Each product includes a batch-specific Certificate of Analysis (COA) with HPLC purity data, mass spectrometry verification, batch numbers, and synthesis information. Third-party testing ensures independent verification.
How should research peptides be stored?
Lyophilized peptides should be stored at -20°C or lower in a dry environment protected from light. Reconstituted peptides require refrigeration at 2-8°C and should be used within the timeframe specified in documentation.
Explore Research-Grade Compounds
All products include third-party testing documentation, batch-specific Certificates of Analysis, and secure checkout. For research use only.
Research Use Only: Products are intended for laboratory and scientific research purposes only. Not for human or veterinary use. By purchasing, you confirm compliance with all applicable regulations.