Ipamorelin vs CJC-1295: GHRP vs GHRH Research
Comparing two distinct peptide classes that target different pathways in growth hormone research applications.
Quick Comparison
| Category | Ipamorelin | CJC-1295 |
|---|---|---|
| Compound Type | Growth hormone releasing peptide (GHRP) | Growth hormone releasing hormone (GHRH) |
| Amino Acid Length | 5 amino acids | 29 amino acids (modified) |
| Mechanism | Ghrelin receptor agonist | GHRH receptor agonist |
| Research Focus | Pulsatile GH release patterns | Sustained GH release patterns |
| Half-Life | ~2 hours | Extended (DAC modification) |
| Purity Standard | ≥98% HPLC verified | ≥98% HPLC verified |
| Availability | 10mg vials | 5mg vials (with Ipamorelin blend) |
What Is Ipamorelin?
Ipamorelin is a synthetic pentapeptide (5 amino acids) that functions as a selective growth hormone releasing peptide (GHRP). It acts as a ghrelin receptor agonist, stimulating the pituitary to release growth hormone in pulsatile patterns.
In laboratory research, Ipamorelin is studied for:
- Selective GH secretagogue activity
- Ghrelin receptor pathway characterization
- Pulsatile hormone release patterns
- Minimal effect on cortisol and prolactin in models
Its selectivity profile makes Ipamorelin particularly valuable for isolated pathway studies without confounding variables from other hormone systems.
What Is CJC-1295?
CJC-1295 is a synthetic analog of growth hormone releasing hormone (GHRH), consisting of 29 amino acids with modifications to extend its biological activity. The DAC (Drug Affinity Complex) version provides significantly extended duration of action.
In research settings, CJC-1295 is studied for:
- GHRH receptor pathway activation
- Sustained growth hormone elevation models
- IGF-1 axis research
- Extended-release peptide pharmacokinetics
The extended half-life of CJC-1295 makes it useful for studying prolonged receptor activation and downstream signaling effects.
Key Differences for Researchers
These compounds represent two distinct approaches to growth hormone pathway research:
Receptor Pathways
Ipamorelin activates the ghrelin (GHS-R1a) receptor, while CJC-1295 targets the GHRH receptor. These distinct pathways offer different research models for understanding GH regulation.
Release Patterns
Ipamorelin research typically shows pulsatile GH release patterns similar to physiological rhythms. CJC-1295 studies often demonstrate more sustained elevation due to its extended half-life.
Selectivity Profile
Ipamorelin is noted in research for its selectivity, with minimal effects on cortisol and prolactin pathways. CJC-1295 as a GHRH analog has a different selectivity profile relevant to its receptor target.
Combination Research
Many research protocols examine both compounds together to study potential synergistic effects when activating both receptor pathways simultaneously, which is why we offer a CJC-1295 + Ipamorelin blend.
Why Documentation & Testing Matter
In research settings, the reliability of results depends entirely on the quality and consistency of materials used. Third-party verification provides an objective baseline for researchers to trust their experimental inputs.
Third-Party Testing
Independent laboratory verification ensures unbiased purity and identity confirmation.
Batch Consistency
Each production batch is individually tested and documented for reproducibility.
≥98% Purity Standard
HPLC and mass spectrometry verification for research-grade quality assurance.
Transparent COAs
Complete Certificates of Analysis available for every product and batch.
Research-Grade Standards from Maple Research Labs
We're committed to providing researchers with consistently high-quality compounds, transparent documentation, and reliable service across Canada.
Canadian-Based Fulfillment
Fast domestic shipping from within Canada, reducing transit times and customs delays.
Independent Lab Testing
Every batch verified by third-party laboratories for purity and identity confirmation.
Research-Only Compliance
Clear labeling and documentation designed for legitimate research applications.
Consistent Quality Standards
Rigorous QC protocols ensure batch-to-batch consistency for reliable research outcomes.
Frequently Asked Questions
What is the difference between GHRP and GHRH peptides?
GHRPs like Ipamorelin work through the ghrelin receptor pathway to stimulate growth hormone release in pulses. GHRHs like CJC-1295 work through the GHRH receptor to amplify and sustain growth hormone secretion. They operate through distinct but complementary mechanisms.
Why are these peptides often studied together?
Researchers frequently examine both compounds because they target different receptor pathways that converge on growth hormone release. Studying them together helps understand potential synergistic effects and pathway interactions.
Are these compounds approved for human use?
No. These are research compounds intended strictly for laboratory investigation. They are not approved for human or veterinary use. All Maple Research Labs products are sold for research purposes only.
What documentation is available?
All products have batch-specific Certificates of Analysis available with HPLC purity verification, mass spectrometry identity confirmation, and synthesis documentation.
How should these peptides be stored?
Lyophilized peptides should be stored at -20°C in a dry environment protected from light. Reconstituted peptides require refrigeration at 2-8°C and should be used within recommended timeframes.
Explore Research-Grade Compounds
All products include third-party testing documentation, batch-specific Certificates of Analysis, and secure checkout. For research use only.
Research Use Only: Products are intended for laboratory and scientific research purposes only. Not for human or veterinary use. By purchasing, you confirm compliance with all applicable regulations.