BPC-157 5MG

BPC-157 peptide Canada 5mg: a synthetic pentadecapeptide derived from human gastric juice protein BPC (Body Protection Compound-157). This research-grade compound is available from Maple Research Labs with greater than 99%+ HPLC-verified purity and a batch-specific Certificate of Analysis (COA) included with every order.

Product Specifications

• CAS Number: 137525-51-0
• Molecular Formula: C62H98N16O22
• Molecular Weight: 1419.53 g/mol
• Purity: >99%+ (HPLC verified)
• Form: Lyophilized powder
• Quantity: 5mg per vial

BPC-157 Peptide Canada Research Summary

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a partial sequence of human gastric juice protein BPC. It consists of 15 amino acids and is stable in human gastric juice, a characteristic that distinguishes it from many other bioactive peptides in preclinical research. The peptide’s sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) was first characterized by research groups investigating cytoprotective properties of gastric juice-derived compounds.

Extensive animal model research has investigated BPC-157’s effects on tissue repair mechanisms. Published studies in rodent models have documented effects on tendon-to-bone healing, ligament recovery, muscle crush injury recovery, and gastrointestinal mucosal integrity. Research has demonstrated involvement of the NO system, growth factor modulation (including VEGF, EGF), and FAK-paxillin signaling pathways.

Mechanism of Action Research

At the molecular level, published research has identified several signaling pathways potentially involved in the biological activities observed in preclinical BPC-157 peptide studies. Key areas of investigation include modulation of the nitric oxide (NO) system through interaction with NOS isoforms, upregulation of growth factor receptors (including VEGFR2 and EGF receptor systems), and engagement of the FAK-paxillin signaling cascade associated with cell migration and adhesion.

In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors. These observations have contributed to ongoing research interest in the compound’s potential interactions with vascular endothelial growth factor pathways.

Preclinical Study Summary

Animal model investigations have explored BPC-157 across multiple tissue types and experimental injury models. Published peer-reviewed studies include research on transected Achilles tendons in rats, quadriceps muscle crush injury models, surgically-induced and chemically-induced gastrointestinal lesions, NSAID-induced mucosal damage models, and ligament transection recovery studies.

The peptide has been examined in over 100 published preclinical studies conducted by multiple independent research groups across several countries. Research has spanned gastrointestinal, musculoskeletal, and neurological model systems.

All published findings referenced here are based exclusively on animal models and in vitro systems. No completed clinical trials in human subjects have been reported in the peer-reviewed literature to date.

References

• Sikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016 (PubMed)

Quality Assurance

BPC-157 peptide from Maple Research Labs undergoes independent third-party HPLC analysis to verify purity exceeding 99%+. The batch-specific Certificate of Analysis (COA) is linked on this product page and includes retention time data, purity percentage, molecular weight confirmation by mass spectrometry, and identity verification.

Storage and Handling

Store lyophilized BPC-157 peptide at -20C for long-term storage. Once reconstituted, store at 2-8C and use within 30 days. Avoid repeated freeze-thaw cycles. Keep away from direct light and moisture.

Shipping

Ships same-day from our Canadian facility. All orders include temperature-controlled packaging.

For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.

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